See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.
View the COMSOL Conference 2019 Collection
Bioscience and Bioengineeringx

Modeling and Simulation of Drug Release through Polymer Matrices new

V. Runkana[1], A. Pareek[1], P. Arora[2]
[1]Tata Consultancy Services, Pune, Maharashtra, India
[2]Indian Institute of Technology Delhi, New Delhi, Delhi, India

Limited drug efficacy, undesirable temporal changes in drug concentration and patient non-compliance due to frequent dosing schedule have given impetus to design of controlled drug release systems [1]. Biodegradable polymers due to their favorable and tunable properties and ... Read More

Multiphysics Modeling of a Grain Storage Chamber new

P. Guha[1], P. Sharma[1], V. Malhotra[1], S. Mishra[1]
[1]CSIR - Central Scientific Instruments Organisation, Chandigarh, India

Proper storage of grains depends on minimizing attacks of insects, fungi, mites, etc. Development of such pests can be controlled by controlling the temperature of the storage chamber. Hence, before designing grain storage chambers, mathematical modeling and numerical simulations should ... Read More

Multiscale Electromagnetic Modeling of Contractions in the Pregnant Uterus new

V. Tidwell[1], P. LaRosa[2], M. Zhang[1], H. Eswaran[3], A. Nehorai[1]
[1]Department of Electrical & Systems Engineering, Washington University in St. Louis, St. Louis, MO, USA
[2]Monsanto Company, Technology Pipeline Solutions, St. Louis, MO, USA
[3]OB/GYN Department, University of Arkansas for Medical Sciences, Little Rock, AR, USA

Uterine contractions during pregnancy are currently poorly understood – experts disagree on the mechanisms by which contractions propagate through the organ and the structural layout of the uterine muscle fibers. We have developed a multi-scale model of the uterus, at the cellular, ... Read More

Microvascular Dysfunction in PAD Patients new

K. Cluff[1], H. Mehraein[1], B. Jayakumar[2]
[1]Department of Bioengineering, Wichita State University, Wichita, KS, USA
[2]Department of Industrial & Manufacturing Engineering, Wichita State University, Wichita, KS, USA

Background: Peripheral arterial disease (PAD) is characterized by atherosclerotic blockages of the arteries supplying the lower extremities, which cause a progressive accumulation of ischemic injury to the skeletal muscles of the lower limbs. Despite revascularization treatment ... Read More

Design of Multiple Ground System for Maternal Defibrillation new

A. Jeremic[1], E. Khoshrowshahli[2]
[1]Electrical & Computer Engineering, McMaster University, Hamilton, ON, Canada
[2]Biomedical Engineering, McMaster University, Hamilton, ON, Canada

Although cardiac arrest may be statistically insignificant event financial and more important emotional costs in such cases are quite devastating. In this paper we study the effects of multiple grounding pads. Namely, we believe that by placing multiple pads in the lower abdominal ... Read More

Conductivity Estimation of Breast Cancer Using COMSOL® Modeling of Microwave Scattering and Frechet Mean Estimate of Covariance new

A. Jeremic[1], E. Khoshrowshahli[2]
[1]Electrical & Computer Engineering, McMaster University, Hamilton, ON, Canada
[2]Biomedical Engineering, McMaster University, Hamilton, ON, Canada

Breast cancer detection is one of the most important problems in health care and it is second most frequent cancer according to WHO. It is recommended that women over fifty or even younger in some cases do a screening test every two years. Besides clinical breast examination, there are ... Read More

Modeling of Hydrogel-Based Controlled Drug Delivery System for Breast Cancer Treatment new

K. Cluff[1], L. Saeednia[2], H. Mehraein [1], R. Asmatulu[2]
[1]Department of Bioengineering, Wichita State University, Wichita, KS, USA
[2]Department of Mechanical Engineering, Wichita State University, Wichita, KS, USA

Polymeric hydrogel is a promising class of drug delivery systems with the controlled release behavior in the body. In-situ forming hydrogels can be injected into the body as a fluid which forms a gel within the body tissue and improve the efficacy of the drugs. Various polymers have been ... Read More

Simulation and Experimental Analysis of Drug Release Rates from Magnetic Nanocomposite Spheres new

L. Saeeednia[1], H. Mehraein[2], F. Abedin[1], K. Cluff[2], R. Asmatulu[1]
[1]Department of Mechanical Engineering, Wichita State University, Wichita, KS, USA
[2]Department of Bioengineering, Wichita State University, Wichita, KS, USA

Targeted drug delivery systems have been wildly studied in cancer therapy due to the toxicity of most of chemotherapeutic drugs. Nanoparticles can be attached to the small molecules of the drugs and serve as drug carriers to deliver the drug molecules into the area of interest. In this ... Read More

Estudo Numérico da Eletroquimioterapia em Tumor Cutâneo com Diferentes Configurações de Eletrodos new

G. Neves[1], D. Suzuki[1], J. Alvim[1], M. Rangel[2]
[1]Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil
[2]Vet Câncer Oncologia Veterinária, São Paulo, SP, Brasil

A eletroquimioterapia é um tratamento de câncer que utiliza a combinação de agentes quimioterápicos e campos elétricos. A base teórica por trás dessa aplicação é a eletroporação. Esse fenômeno biológico consiste na abertura de poros na membrana celular devido à aplicação de pulsos ... Read More

Performance of a Miniaturized Hydrocyclone for the Isolation of Schistosoma Mansoni Eggs new

C. Soares[1], N. Padoin[1], F. Montalvo[2], D. Cobra[2]
[1]Federal University of Santa Catarina, Florianópolis, SC, Brazil
[2]CERTI Foundation, Florianópolis, SC, Brazil

Schistosoma mansoni parasites affect million people worldwide. The intensity of the infection can be evaluated by the number of eggs present in the stool of an infected individual. The application of the traditional methods has been regarded as impractical in developing areas and there ... Read More