S. Raveendran, S. Sukuvihar, S. Kumar, and T. Maekawa
• Bionanotechnology is a stream of modern science that deals with the study of biotechnology & nanotechnology applications. • Drug delivery applications as a key area of research attains more critical approaches where the role of nanoparticles are inevitable. • Biocompatible, non-cytotoxic hybrid mauran- chitosan nanoparticles has been synthesized and the drug release kinetics were ...
N. Mane, A. Gaikwad
Department of Instrumentation, Cummins College of Engineering, Pune, Maharashtra, India
Micro electro-mechanical system (MEMS) is rapidly growing area of interest for a broad spectrum of applications. One particularly fast-growing area is biomedical applications for micromaching technologies. One application of interest to the biomedical industry is the development of microneedles. MEMS technology brings new means for biomedicine field. Patch-based transdermal drug delivery offers ...
K. Cluff, H. Mehraein, B. Jayakumar
Department of Bioengineering, Wichita State University, Wichita, KS, USA
Department of Industrial & Manufacturing Engineering, Wichita State University, Wichita, KS, USA
Background: Peripheral arterial disease (PAD) is characterized by atherosclerotic blockages of the arteries supplying the lower extremities, which cause a progressive accumulation of ischemic injury to the skeletal muscles of the lower limbs. Despite revascularization treatment intervention some PAD patients require follow up secondary treatment due to a continued decline in limb function, ...
Simulations of Heat and Mass Transport During Biomass Conversion Processes Using 3D Biomass Particle Models with Realistic Morphology and Resolved Microstructure
P. Ciesielski, M. Crowley, L. Thompson, B. Donohoe, D. Robichaud, A. Sanders, M. Nimlos, T. Foust
Biosciences Center, National Renewable Energy Laboratory, Golden, CO, USA
National Bioenergy Center, National Renewable Energy Laboratory, Golden, CO, USA
Quantum Electronics & Photonics Division, National Institute of Standards & Technology, Boulder, CO, USA
Predictive simulations of biomass conversion processes will improve their technical performance and reduce economic uncertainty surrounding industrialization of biofuels production. The majority of present conversion simulations treat the biomass feedstock with simplifying assumptions that neglect important characteristics that are unique to biomass particles. These characteristics, including ...
R. Samso, N. Forquet, P. Molle, J. Garcia
Department of Hydraulic, Maritime and Environmental Engineering, Universitat Politècnica de Catalunya-BarcelonaTech, Barcelona, Spain
IRSTEA, Freshwater Systems, Ecology and Pollution Research Unit, Villeurbanne, France
Horizontal-Flow Constructed Wetlands (HFCWs) are a particular type of biofilter, and as such they rely mostly on the activity of bacterial communities to treat wastewater. Bacterial growth in HFCWs induces dramatic changes in its hydraulic and hydrodynamic behaviour (bioclogging), which may eventually result in overland flow of wastewater. Consequently, clogging is the main cause of premature ...
School of Mechanical Engineering, University of Birmingham, Birmingham, United Kingdom
A device for monitoring the oxygen consumption of cells has been developed, which consists of two parts; a cell culturing platform (CCP) and an oxygen sensing chip. The CCP possesses inlet and outlet pipes to direct the fluid under the test to the cell culturing chamber through the inlet pipe and goes out of the outlet pipe after being partially consumed by the cells. In this abstract, the oxygen ...
A. Di Carlo, V. Sansalone, A. Tatone, and V. Varano
Modelling and Simulation Lab, Università Roma Tre, Roma, Italy
Laboratoire de Mécanique Physique, Université Paris Est, Paris, France
DISAT, Università degli Studi dell’Aquila, L'Aquila, Italy
We present a mechanical model a growing spherical shell suitable for predicting the evolution of a Saccular Cerebral Artery Aneurysms (SCAA). It relies basically on the Kröner-Lee decomposition, used to describe the interplay between the current and the relaxed configuration of body elements. Rupture or stabilization of a SCAA are the end effect of a number of biological mechanisms, still poorly ...
Q.A. Chaudhry, M. Hanke, and R. Morgenstern
School of Computer Science and Communication, Royal Institute of Technology, Stockholm, Sweden
Karolinska Institutet, Stockholm, Sweden
The mathematical modeling of the diffusion and reaction of toxic compounds in mammalian cells is tough task due to their very complex geometry. The heterogeneity of the cell, particularly the cytoplasm, and the variation of the cellular architecture, greatly affects the behavior of these toxic compounds. Homogenization techniques have been implemented for the numerical treatment of the model. ...
New York University, New York, USA
Computational models of biological systems are becoming more and more common in medical research areas. Evidence of this can be found by examining the number of articles containing the term “finite element” in the expansive National Institutes of Health (NIH) digital research archive PubMed. Numerical modeling of biological systems allows the execution of “computational ...
H.C. Wong, K.N. Cho, and W.C. Tang
Department of Biomedical Engineering, University of California, Irvine, California, USA
Atherosclerosis causes the deposition of plaque on the inner walls of arteries, which leads to restricted blood flow. Using the balloon angioplasty procedure, stents can be inserted and expanded in the atherosclerotic artery. We used COMSOL Multiphysics Structural Mechanics, Solid Stress-Strain module to perform static, large deformation analyses. Our results show that lower stent stresses were ...